Stochastic modelling of memory effects on the Hunchback gene activation in the fruit fly embryo
نویسندگان
چکیده
The work has been carried out at the Institute Curie in collaboration between the group of Maxime Dahan and the group of Natalie Dostatni. The Curie Institute is located in Rue de Pierre et Marie Curie and at Orsay. The institute is principally devoted to research on cancer through medicine, biology and biophysics. In addition, many groups at the Curie Institute are working on more fundamental research. The AXOMORPH work group (funded by the ANR) is a research collaboration which focuses on the dynamic and quantitative understanding of axis formation in Drosophila. The group includes biologists (Nathalie Dostatni, UMR 218) who gather data and physicists (Mathieu Coppey, UMR 168, Teresa Ferraro, UMR 168 and ENS Paris, and Aleksandra Walczak, ENS Paris) who analyse the data. The supervisor for this internship has been
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Mid-Embryo Patterning and Precision in Drosophila Segmentation: Krüppel Dual Regulation of hunchback
In early development, genes are expressed in spatial patterns which later define cellular identities and tissue locations. The mechanisms of such pattern formation have been studied extensively in early Drosophila (fruit fly) embryos. The gap gene hunchback (hb) is one of the earliest genes to be expressed in anterior-posterior (AP) body segmentation. As a transcriptional regulator for a number...
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تاریخ انتشار 2013